The concomitant utilization of METHADOSE with all cytochrome P450 3A4, 2B6, 2C19, 2C9 or 2D6 inhibitors could result in an increase in methadone plasma concentrations, which could trigger most likely fatal respiratory depression. Additionally, discontinuation of concomitantly utilised cytochrome P450 3A4, 2B6, 2C19, or 2C9 inducers may additionally… Read More